Regulation of kidney function
1)Renin Angiotensinogen Aldosterone System :
The functioning of the kidneys is efficiently monitored and regulated by hormonal feedback mechanisms involving the hypothalamus, JGA and to a certain extent, the heart.Osmoreceptors in the body are activated by changes in blood volume,body fluid volume and ionic concentration.An excessive loss of fluid from the body can activate these receptors which stimulate the hypothalamus release antidiuretic hormone (ADH) or vasopressin from the neurohypophysis. ADH facilitates water reabsorption from latter parts of the tubule, thereby preventing diuresis. An increase in body fluid volume can switch off the osmoreceptors and suppress the ADH release to complete the feedback. ADH can also affect the kidney function by its constrictory effects on blood vessels. This causes an increase in blood pressure. An increase in blood pressure can increase the glomerular blood flow and thereby the GFR.The JGA plays a complex regulatory role. A fall in glomerular...